Gut bacteria capsules may shield heart surgery patients from organ damage
NCT ID NCT04444362
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving patients capsules containing gut bacteria (called Probacine) before and after heart surgery can reduce gut injury and organ failure. Researchers will enroll 500 adults undergoing cardiovascular surgery. The goal is to see if changing the gut microbiome can improve recovery and lower death rates.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Intestinal Microbiota Transplant (IMT) Capsules
What this could lead to
If it works, this could point toward a simple way to protect the gut and organs after heart surgery, reducing complications.
What could go wrong
This is an early-stage trial with no phase designation, so results are uncertain. The intervention involves transplanting gut bacteria, which carries unknown risks.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beijing Anzhen Hospital
Beijing, Beijing Municipality, China
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Shanghai East Hospital, Tongji University
Shanghai, China
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The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
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The First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, 210029, China
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West China Hospital of Sichuan University
Chengdu, Sichuan, China