New study aims to predict who can skip surgery for rectal cancer
NCT ID NCT05524012
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This pilot study is testing whether regular MRI scans and blood tests can accurately track how rectal cancer responds to pre-surgery treatment. The goal is to develop a way to predict complete remission without needing surgery. Forty adults with locally advanced rectal cancer will be followed to see if these non-invasive tools can guide personalized treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a non-invasive way to predict which patients with rectal cancer can avoid surgery and still achieve a cure.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to everyone. The approach is still experimental and needs larger trials to confirm.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Radiotherapy and Radiation Oncology, Jena University Hospital
Jena, Germany