LOCALLY ADVANCED RECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED RECTAL CARCINOMA explained in plain language.
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Heat therapy boosts rectal cancer treatment in new trial
Disease control Recruiting nowThis phase 3 trial tests whether adding a special heat treatment (modulated electro-hyperthermia) to standard therapy helps shrink tumors more in adults with locally advanced rectal cancer. About 126 participants will be randomly assigned to receive standard therapy alone or with…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE3 • Sponsor: Shih-Kai Hung • Aim: Disease control
Last updated May 17, 2026 09:17 UTC
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New triple therapy aims to shrink hard-to-treat rectal cancers before surgery
Disease control Recruiting nowThis study tests whether combining an immunotherapy drug (serplulimab) with chemotherapy (CAPEOX) and an anti-inflammatory drug (celecoxib) can shrink advanced rectal cancers before surgery. The trial enrolls 50 adults with a specific type of rectal cancer (pMMR/MSS) that usually…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Immunotherapy boost may help rectal cancer patients avoid surgery
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug tislelizumab to standard chemoradiation can improve outcomes for people with locally advanced rectal cancer. About 375 adults will receive either chemoradiation alone or combined with tislelizumab before surgery. The goal is …
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Beijing Friendship Hospital • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New combo may let rectal cancer patients skip surgery
Disease control Recruiting nowThis early-phase study tests whether a short course of radiation followed by chemotherapy can shrink tumors enough to avoid surgery in people with stage II-III rectal cancer. The goal is to preserve the rectum and improve quality of life. About 25 adults with locally advanced rec…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 07, 2026 18:42 UTC
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New PET scan could sharpen view of rectal cancer during treatment
Diagnosis Recruiting nowThis early study tests a special PET scan that uses a radioactive tracer (64Cu-M5A) to highlight rectal cancer cells. The goal is to see if this scan can show tumor extent and response better than standard scans in 15 adults with locally advanced rectal cancer before and after ch…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated May 17, 2026 09:19 UTC