LOCALLY ADVANCED RECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED RECTAL CARCINOMA explained in plain language.
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New combo treatment aims to spare rectal cancer patients from surgery
Disease control Recruiting nowThis early-stage trial is testing whether a short, intense course of radiation followed by several months of chemotherapy can effectively shrink rectal tumors. The main goal is to see if this approach can eliminate the cancer enough that patients can avoid having their rectum sur…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Four-Drug attack tested to shrink rectal tumors before surgery
Disease control Recruiting nowThis study is testing a four-drug combination given before surgery for locally advanced rectal cancer. The goal is to see if adding an immunotherapy drug (serplulimab) and an anti-inflammatory drug (celecoxib) to standard chemotherapy can shrink tumors more effectively. Researche…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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New hope for rectal cancer: adding immunotherapy to standard treatment
Disease control Recruiting nowThis study is testing if adding an immunotherapy drug (tislelizumab) to standard chemotherapy and radiation before surgery works better for people with locally advanced rectal cancer. It will compare the new combination against the standard treatment alone in about 375 participan…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Beijing Friendship Hospital • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Heating tumors to boost cancer treatment
Disease control Recruiting nowThis study is testing if adding a special heat therapy to standard treatment helps shrink tumors more effectively in adults with locally advanced rectal cancer. Researchers will compare standard treatment alone to standard treatment plus targeted heat sessions delivered twice a w…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE3 • Sponsor: Shih-Kai Hung • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New scan could sharpen the picture for rectal cancer treatment
Diagnosis Recruiting nowThis small, early study is testing a new type of imaging scan to see if it can provide a clearer picture of rectal cancer tumors. The scan uses a radioactive tracer that attaches to a protein common in these cancers. Researchers want to see if this scan, given before and after st…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Mar 27, 2026 12:41 UTC