LOCALLY ADVANCED RECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED RECTAL CARCINOMA explained in plain language.
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Could less be more? new study tests smaller surgery for rectal cancer
Disease control OngoingThis study looks at whether people with advanced upper rectal cancer can have a smaller surgery after receiving pre-treatment (chemotherapy or radiation). The goal is to remove less healthy tissue while still being safe and effective. About 874 adults will be randomly assigned to…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: NA • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New chemo cocktail may help rectal cancer patients skip surgery
Disease control OngoingThis study tests whether a three-drug chemotherapy combination (FOLFIRINOX) works better than standard two-drug combinations (FOLFOX or CAPOX) after radiation for stage II-III rectal cancer. The goal is to see if more patients can achieve a complete response, potentially avoiding…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New study aims to tailor rectal cancer therapy with cutting-edge imaging and liquid biopsy
Knowledge-focused OngoingThis pilot study is testing whether advanced MRI scans and blood tests can help doctors adjust treatment for people with locally advanced rectal cancer. The goal is to see if these tools can predict which patients respond well enough to avoid surgery. Forty participants will be f…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Sponsor: Jena University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 04:32 UTC
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Exercise before and during radiotherapy: a new hope for rectal cancer patients?
Knowledge-focused TerminatedThis study looked at whether a 7-week exercise program (aerobic and resistance training) could help people with locally advanced rectal cancer who are receiving short-course radiotherapy. The goal was to see if such a program is practical and acceptable to patients. However, the …
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: NA • Sponsor: University of Hull • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC