Jena University Hospital

This study aims to find the best way to prevent strokes in people with a common heart rhythm problem (atrial fibrillation) who have already suffered a dangerous brain bleed. Researchers are comparing a one-time heart implant that closes off a small pouch in the heart to long-term…

This study aims to determine if treating herpes simplex virus (HSV) with the drug acyclovir helps critically ill pneumonia patients on ventilators survive. Researchers will randomly assign 616 ICU patients who have both pneumonia and HSV detected in their lungs to receive either …

This study is testing if a drug called bortezomib, already used for a type of blood cancer, can help people with severe autoimmune encephalitis. In this condition, the body's immune system mistakenly attacks the brain. The trial will see if bortezomib safely reduces these harmful…

This study aims to understand how well common blood tests (troponin and CK-MB) actually measure heart muscle damage after valve surgery. Researchers will enroll 100 adults having isolated aortic or mitral valve surgery, comparing their blood test results with detailed heart MRI s…

This study aims to understand if analyzing bile acid patterns in pregnant women with intrahepatic cholestasis of pregnancy (ICP) can help predict risks to the baby. Researchers will compare blood and stool samples from women with ICP, healthy pregnant women, and healthy non-pregn…