Could bile acid fingerprints prevent stillbirths in pregnancy cholestasis?
NCT ID NCT07428226
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study is looking at pregnant women with intrahepatic cholestasis of pregnancy (ICP), a liver condition that raises bile acids and can harm the baby. Researchers want to see if measuring specific bile acid types in the mother's and baby's blood can help predict serious complications like stillbirth. They will also check stool samples, heart rate monitoring, and ultrasound. The study compares three groups: women with ICP, healthy pregnant women, and healthy non-pregnant women.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better predict which pregnancies are at highest risk for stillbirth and other complications, leading to more targeted monitoring.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find clear patterns that improve prediction, and results may not apply to all populations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Klinik für Geburtsmedizin, Universitätsklinikum Jena
RECRUITINGJena, Thuringia, 07747, Germany
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