New hope for Moms-to-Be: drug targets dangerous pregnancy itch

NCT ID NCT07389031

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a drug called maralixibat in 28 pregnant women with intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes severe itching and high bile acids. The main goal is to see if the drug is safe and tolerable for both mother and baby. Researchers will also check if it helps reduce itching and lower bile acid levels.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Birmingham Womens and Childrens NHS Foundation Trust

    Birmingham, B15 2TG, United Kingdom

  • Guy's and St Thomas' NHS Foundation Trust

    London, SE 1 7EH, United Kingdom

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