Can counseling keep homeless youth off opioids?

NCT ID NCT06311838

Recruiting now Prevention Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests two counseling programs—one focused on motivation and coping skills, the other on strengths and advocacy—to prevent opioid misuse in 300 homeless youth aged 14-24. Participants are randomly assigned to one of the programs or standard services, and tracked for two years. The goal is to see which approach best reduces substance use and improves mental health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Motivational Interviewing/Community Reinforcement Approach (MI/CRA) and Strengths-Based Outreach and Advocacy (SBOA)
What this could lead to: If successful, this could provide an effective, scalable program to prevent opioid addiction and improve mental health among homeless youth.
What could go wrong: This is an early-stage trial with 300 participants, so results may not apply to all homeless youth. The interventions are behavioral and may not work for everyone.

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Conditions

The condition(s) this trial relates to.

mental disorder Risk-Taking substance-related disorder opiate dependence prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DUAL DIAGNOSIS HOMELESSNESS HOUSING PROBLEMS MENTAL DISORDER IN ADOLESCENCE OPIOID-USE DISORDER RISK BEHAVIOR

Can counseling keep homeless youth off opioids?

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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