New radiation combo aims to shrink sarcomas before surgery
NCT ID NCT07501026
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase II trial is testing whether a special type of radiation therapy (SFRT) given before surgery can improve outcomes for people with large soft tissue sarcomas (at least 5 cm) in the limbs or trunk. About 22 adults will receive 5 doses of SFRT, then have surgery about a week later. Researchers will track how many patients are cancer-free after one year, how well the tumor responds, and any side effects. Blood samples will also be taken to study how the immune system reacts.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
spatially fractionated radiation therapy (SFRT)
What this could lead to
If successful, this approach could improve disease-free survival and tumor response before surgery for large soft tissue sarcomas, potentially offering a new standard preoperative option.
What could go wrong
This is a small, early-phase (phase II) trial with only 22 participants, so results may not apply broadly. Radiation side effects and surgical complications are possible, and the benefit over current treatments is not yet proven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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2nd Affiliated Hospital, School of Medicine
RECRUITINGHangzhou, Zhejiang, 310000, China
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••