Can immune and imaging clues predict heart valve disease progression?
NCT ID NCT05851209
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study investigates why some people with moderate aortic valve stenosis get worse while others remain stable. Researchers will analyze immune system markers and detailed heart images from about 938 participants to find patterns that predict disease progression. The goal is to identify high-risk patients earlier and potentially guide future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors identify which patients with moderate aortic stenosis are at highest risk of worsening, enabling earlier intervention.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly improve health. The findings may not lead to new therapies or change current care.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital Cologne
RECRUITINGCologne, 50937, Germany
Contact
Contact Email: •••••@•••••
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University-Hospital Bonn
RECRUITINGBonn, 53127, Germany
Contact Email: •••••@•••••
Contact
Contact
Contact Email: •••••@•••••
Contact
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University-Hospital Düsseldorf Division of Cardiology, Pulmonary Disease and Vascular Medicine
RECRUITINGDüsseldorf, 40225, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact