New hope for OCD? brain zaps plus therapy put to the test

NCT ID NCT07146438

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a noninvasive brain stimulation technique called repetitive Transcranial Magnetic Stimulation (rTMS) can boost the effects of a type of talk therapy (Exposure and Response Prevention) for people with obsessive-compulsive disorder (OCD) that hasn't improved with standard treatment. About 48 adults with OCD will receive rTMS along with either the therapy or supportive counseling. Researchers will also use wearable devices and brain scans to track how well people respond, aiming to find better ways to personalize OCD care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

repetitive Transcranial Magnetic Stimulation (rTMS) device

What this could lead to

If successful, this could point toward a more personalized, effective treatment for people with OCD that hasn't responded to standard therapy.

What could go wrong

This is a small, early-stage study with only 48 participants, so results may not apply to everyone. The combination of rTMS and therapy may not work better than therapy alone, and rTMS can cause mild side effects like headache or scalp discomfort.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

obsessive-compulsive disorder obsessive-compulsive personality disorder psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Southern California Health Sciences Campus

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact