Targeted drug trial aims to outperform chemo for tough lung cancer
NCT ID NCT04222972
Summary
This study compared a new targeted drug called pralsetinib against standard chemotherapy for people with advanced lung cancer that has spread and carries a specific genetic change called a RET fusion. The trial involved 223 participants worldwide who had not yet received treatment for their advanced cancer. Researchers measured whether the targeted drug could help patients live longer without their cancer getting worse compared to chemotherapy.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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?zmir Medical Point
Kar?iyaka, 35575, Turkey (Türkiye)
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A.O.U. INTEGRATA DI VERONA-Ospedale Civile Maggiore Borgo Trento
Verona, Veneto, 37126, Italy
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AZ. Ospedaliera San Giovanni - Addolorata
Rome, Lazio, 00184, Italy
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Adana City Hospital, Medical Oncology
Adana, 01060, Turkey (Türkiye)
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Ankara Bilkent City Hospital
Ankara, 06490, Turkey (Türkiye)
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Asan Medical Center
Seoul, 05505, South Korea
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Asklepios-Fachkliniken Muenchen-Gauting
Gauting, 82131, Germany
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Azienda Ospedaliera Universitaria Pisana - Ospedale Cisanello
Pisa, Tuscany, 56124, Italy
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CHRU Lille Service de Pneumologie et Oncologie Thoracique
Lille, 59000, France
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CHU Strasbourg - Nouvel Hopital Civil
Strasbourg, 67091, France
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CHU de Toulouse - Hôpital Larrey
Toulouse, 31100, France
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Centro Oncologico Riojano Integral (CORI)
La Rioja, F5300COE, Argentina
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Christie Hospital Nhs Trust
Manchester, M2O 4BX, United Kingdom
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Clinica CIMCA
San José, 10103, Costa Rica
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Complejo Hospitalario Universitario A Coruña
A Coruña, LA Coruna, 15006, Spain
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Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Lombardy, 20133, Italy
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Guys & St Thomas Hospital
London, SE1 9RT, United Kingdom
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Health Pharma Professional Research
Mexico City, Mexico CITY (federal District), 03100, Mexico
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Hemato Oncología de Panamá Especializada
Panama City, 0801, Panama
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Hopital Bichat Claude Bernard
Paris, 75018, France
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Hopital Tenon
Paris, 75970, France
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Hopital de Pontchaillou
Rennes, 35033, France
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Hosp Clinico Univ Lozano Blesa
Zaragoza, 50009, Spain
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Hospital A. C. Camargo
São Paulo, São Paulo, 01509-010, Brazil
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Hospital Britanico
Buenos Aires, C1280AEB, Argentina
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Hospital General Universitario Gregorio Marañon
Madrid, 28007, Spain
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Hospital Ramon y Cajal
Madrid, 28034, Spain
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Hospital Regional Universitario de Malaga
Málaga, 29010, Spain
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Hospital Sao Lucas - PUCRS
Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario Marques de Valdecilla
Santander, Cantabria, 39008, Spain
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Hospital de Madrid Norte Sanchinarro- Centro Integral Oncologico Clara Campal
Madrid, 28050, Spain
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Hôpital Ambroise Paré - Boulogne-Billancourt
Boulogne-Billancourt, 92100, France
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Hôpital Louis Pradel, Hospices Civils de Lyon
Bron, 69677, France
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IOV - Istituto Oncologico Veneto - IRCCS
Padua, Veneto, 35128, Italy
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IPO do Porto
Porto, 4200-072, Portugal
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IRCCS Giovanni Paolo II Istituto Oncologico
Bari, Apulia, 70124, Italy
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Ico Rene Gauducheau
Saint-Herblain, 44805, France
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Insititut Catala D'Oncologia
L'Hospitalet de Llobregat, Barcelona, 08908, Spain
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Institut Bergonie CLCC Bordeaux
Bordeaux, 33000, France
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Institut Gustave Roussy
Villejuif, 94805, France
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Institut Paoli Calmettes
Marseille, 13273, France
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Irccs Ospedale San Raffaele
Milan, Lombardy, 20132, Italy
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Istituto Europeo Di Oncologia
Milan, Lombardy, 20141, Italy
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Istituto Nazionale Tumori Regina Elena
Rome, Lazio, 00144, Italy
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Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale
Naples, Campania, 80131, Italy
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Juntendo University Hospital
Tokyo, 113-8431, Japan
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Kansai Medical University Hospital
Osaka, 573-1191, Japan
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Karolinska Universitetssjukhuset, Solna
Stockholm, 171 76, Sweden
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Klinik Schillerhöhe
Stuttgart, 70376, Germany
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Kyushu University Hospital
Fukuoka, 812-8582, Japan
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Leicester Royal Infirmary
Leicester, LE1 5WW, United Kingdom
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Leopoldina-Krankenhaus Medizinische Klinik II
Schweinfurt, 97422, Germany
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Maastricht University Medical Center
Maastricht, 6229 HX, Netherlands
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NKI/AvL
Amsterdam, 1066 CX, Netherlands
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Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad
Warsaw, 02-781, Poland
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National Cancer Center
Goyang-si, 10408, South Korea
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National Hospital Organization Himeji Medical Center
Hyōgo, 670-8520, Japan
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National Hospital Organization Yamaguchi - Ube Medical Center
Yamaguchi, 755-0241, Japan
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Osaka International Cancer Institute
Osaka, 541-8567, Japan
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Oslo universitetssykehus HF, Ullevål, Kreftsenteret
Oslo, 0450, Norway
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Ospedale Clinicizzato SS Annunziata
Chieti, Abruzzo, 66100, Italy
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Ospedale Provinciale Santa Maria Delle Croci
Ravenna, Emilia-Romagna, 48100, Italy
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Pius-Hospital
Oldenburg, 26121, Germany
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Royal Marsden Hospital
London, SW3 6JJ, United Kingdom
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Royal North Shore Hospital
St Leonards, New South Wales, 2065, Australia
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Seoul National University Hospital
Seoul, 03080, South Korea
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Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
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St. James Hospital
Dublin, D08 HNY1, Ireland
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The Cancer Institute Hospital of JFCR
Tokyo, 135-8550, Japan
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UZ Antwerpen
Edegem, 2650, Belgium
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UniversitätsSpital Zürich
Zurich, 8091, Switzerland
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Universitätsklinikum Carl Gustav Carus, Medizinische Klinik I, Pneumologie MK1-A13
Dresden, 01307, Germany
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Velindre Cancer Centre
Cardiff, CF14 2TL, United Kingdom
Conditions
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