THORACIC NEOPLASMS

This study is for people with advanced non-small cell lung cancer whose tumors have high PD-L1 levels. Researchers want to see if a blood test that measures tumor DNA (ctDNA) can help decide whether to add chemotherapy to the immunotherapy drug cemiplimab. About 63 participants w…

This study tests a drug called tarlatamab as a maintenance therapy for people with limited-stage small-cell lung cancer who cannot receive standard concurrent chemo-radiotherapy. After completing sequential chemo-radiation or chemotherapy alone, participants whose cancer has not …

This study tests a drug called teniposide in 15 people with advanced small cell lung cancer that has a specific gene change (c-Myc) and has stopped responding to standard treatments. The goal is to see if the drug can shrink tumors and control the disease. Participants must be in…

This study tests a drug called mecapegfilgrastim in 30 adults with lung or esophageal cancer who are getting chemotherapy and radiation. The goal is to see if it can safely prevent or reduce myelosuppression, a condition where the body makes fewer blood cells. Participants will b…

This study aims to see how well a robotic system works for finding and taking samples from suspicious spots in the lungs. It will observe 3,000 adults who are already scheduled to have this procedure as part of their regular care. The main goal is to measure how often the biopsy …

This study tests whether combining three treatments—a spine-stabilizing procedure, radiofrequency ablation (using heat to destroy tumor tissue), and radiation therapy—can better relieve pain in people with cancer that has spread to the middle or lower back. All 70 participants wi…

This study tests whether a special nerve block injection given before lung surgery can lower pain and the amount of pain medicine patients need afterward. About 70 adults having lung tumor removal will take part. Researchers will track pain scores and medication use for 24 hours …

This study tests whether a diet rich in medium-chain triglycerides (MCTs) can help people recover faster after lung surgery. MCTs are fats that bypass the lymphatic system, potentially reducing fluid buildup and shortening hospital stays. The trial will enroll 210 adults undergoi…