New combo tackles back pain from spine tumors

NCT ID NCT07479199

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether combining three treatments—kyphoplasty (spine stabilization), radiofrequency ablation (heat to destroy tumor tissue), and standard radiation—can better reduce pain from spine tumors. About 70 adults with cancer that has spread to the middle or lower back and who have moderate to severe pain will receive all three treatments. The main goal is to see how much pain drops one month after radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiofrequency ablation (Osteocool system) and kyphoplasty procedure

What this could lead to

If successful, this combination could offer better pain relief for people with cancer that has spread to the spine, improving quality of life.

What could go wrong

This is a small, single-arm study (70 people) with no comparison group, so results may not prove the combination is better than radiation alone. Pain relief varies and risks include procedure-related complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm in the spinal cord neoplasm neoplasm of thorax Pain Thoracic Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UNC Hospitals

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact