New combo tackles back pain from spine tumors

NCT ID NCT07479199

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether combining three treatments—kyphoplasty (spine stabilization), radiofrequency ablation (heat to destroy tumor tissue), and standard radiation—can better reduce pain from spine tumors. About 70 adults with cancer that has spread to the middle or lower back and who have moderate to severe pain will receive all three treatments. The main goal is to see how much pain drops one month after radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiofrequency ablation (Osteocool system) and kyphoplasty procedure
What this could lead to
If successful, this combination could offer better pain relief for people with cancer that has spread to the spine, improving quality of life.
What could go wrong
This is a small, single-arm study (70 people) with no comparison group, so results may not prove the combination is better than radiation alone. Pain relief varies and risks include procedure-related complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UNC Hospitals

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

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