Motorized brace aims to unload painful knees without surgery

NCT ID NCT07673328

Recruiting now Symptom relief Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study tests a modular, powered leg brace (exoskeleton) designed to assist knee movement and reduce pain in people with knee osteoarthritis. The brace provides a small amount of torque to help the joint, potentially lowering muscle effort and painful loads on the knee. Researchers will measure changes in pain, muscle activity, and walking speed in up to 65 participants, including both healthy adults and those with knee OA.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Modular powered orthosis (exoskeleton)
What this could lead to: If successful, this device could offer a non-drug, non-surgical way to reduce knee pain and improve mobility for people with knee osteoarthritis.
What could go wrong: This is an early feasibility study with only 65 participants, so results may not apply to everyone. The device may not reduce pain enough to be practical.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOWER-LIMB ORTHOSES OSTEOARTHRITIC KNEE PAIN OSTEOARTHRITIS (OA) OF THE KNEE

Contacts and locations

Locations

Rehab Lab
RECRUITING

Ann Arbor, Michigan, 48109, United States

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