Can head position and cooling boost brain recovery after cardiac arrest?

NCT ID NCT07769086

NEW Not yet recruiting Disease control Sponsor: Kagawa University Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether specific care strategies used in the intensive care unit after cardiac arrest can improve neurological recovery and survival. Adults who remain comatose after their heartbeat is restored will be cared for using either head elevation or a near-supine position, and either targeted cooling or fever prevention. The study compares these approaches to see which may lead to better brain function and quality of life at 30 and 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Head positioning (head elevation vs. near-supine) and temperature control (targeted hypothermia vs. normothermia/fever prevention) during post-cardiac arrest intensive care
What this could lead to: If successful, this could identify simple, low-cost care strategies that improve brain recovery and survival for people who remain comatose after cardiac arrest.
What could go wrong: The trial is early and uses hospital-level randomization, so results may be influenced by differences in care quality. The interventions may not improve outcomes and could carry risks like complications from cooling or positioning.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac arrest post-cardiac arrest syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC ARREST (CA) POST CARDIAC ARREST SYNDROME

Contacts and locations

Locations

Aso Iizuka Hospital

Iizuka, Fukuoka, 8208505, Japan
Chiba Kaihin Municipal Hospital

Chiba, Chiba, 2610012, Japan
Hiroshima University Hospital

Hiroshima, Hiroshima, 7348551, Japan
Hyogo Emergency Medical Center

Kobe, Hyōgo, 651-0073, Japan
Kagawa University Hospital

Kita-gun, Kagawa-ken, 761-0701, Japan
Kyoto Katsura Hospital

Kyoto, Kyoto, 6158256, Japan
Musashino Red Cross Hospital

Musashino, Tokyo, 1800023, Japan
National Hospital Organization Sendai Medical Center

Sendai, Miyagi, 9838520, Japan
Nippon medical school hospital

Bunkyō-Ku, Tokyo, 113-8603, Japan
Okayama University Hospital

Okayama, Okayama-ken, 7008558, Japan
TMG Asaka Medical Center

Asaka, Saitama, 3510023, Japan
Tokyo Metropolitan Bokutoh Hospital

Sumida-ku, Tokyo, 1308575, Japan

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