Platelet injections may ease jaw arthritis pain
NCT ID NCT06573502
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether injecting platelet-rich plasma (PRP) with or without platelet-rich fibrin (PRF) can reduce pain and improve jaw movement in adults with temporomandibular joint osteoarthritis. 42 participants received either a combination of PRP and PRF, PRP alone, or PRF alone. The main goal was to measure pain severity and how wide the mouth could open.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
platelet-rich plasma and platelet-rich fibrin injections
What this could lead to
If one of these treatments works well, it could offer a simple injection-based option to ease jaw pain and improve mouth opening for people with TMJ osteoarthritis.
What could go wrong
This is a small, completed trial with only 42 participants, so results may not apply to everyone. The treatments are not yet proven to be better than standard care, and benefits may be modest.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cairo university
Cairo, Egypt