Tiny plastics, big gut worry? new study probes link to bowel disease

NCT ID NCT06001450

Recruiting now Knowledge-focused Sponsor: Icahn School of Medicine at Mount Sinai Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The PLANET study is looking at whether tiny plastic particles in our environment can trigger gut inflammation and raise the risk of inflammatory bowel disease (IBD). Researchers will measure microplastics in stool samples from pregnant women, their healthy relatives, and people with Crohn's disease. They will also analyze gut bacteria and inflammation markers to better understand how pollutants may contribute to IBD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify environmental triggers for inflammatory bowel disease, pointing toward prevention strategies.
What could go wrong: This is an early observational study with only 46 participants, so findings may not apply broadly. It measures associations, not cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHNS DISEASE INFLAMMATORY BOWEL DISEASE PREGNANCY

Contacts and locations

Locations

Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10128, United States

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