CROHNS DISEASE

This early-stage study is testing a new cell therapy called TRX103 for people with moderate-to-severe Crohn's disease that hasn't responded to at least two standard treatments. Researchers will give different doses to 39 participants to check safety and see if it reduces gut infl…

This study is checking the long-term safety of guselkumab in children who already benefited from it in previous studies. It includes 196 children with Crohn's disease, ulcerative colitis, or juvenile psoriatic arthritis. The main goal is to see if the drug remains safe when used …

This study aims to see if a simpler, portable ultrasound scan can be as useful as a colonoscopy for monitoring ulcerative colitis and Crohn's disease, while also having a much smaller environmental footprint. Researchers will compare the two methods in 200 patients to measure bot…

This study aims to understand if tiny plastic particles in our environment affect gut bacteria and inflammation, potentially increasing the risk for Crohn's disease and other bowel conditions. Researchers will analyze stool samples from pregnant women with Crohn's, healthy women,…

This study aims to find the best way to check for magnesium deficiency in people with gut diseases like Crohn's, colitis, or an ileostomy. Researchers will compare several different measurement methods, including blood tests, urine tests, and optional muscle biopsies, in 120 part…

This study aims to create new measurement tools so that people with Crohn's disease who have a permanent ileostomy can finally be included in future treatment trials. Researchers will work with about 50 participants to develop two tools: one based on patient interviews about thei…