CROHNS DISEASE

This study tests a new treatment called TRX103 for people with moderate to severe Crohn's disease that hasn't improved with other treatments. The goal is to see if TRX103 is safe and can reduce gut inflammation. About 39 adults aged 18 to 65 will receive a single infusion of TRX1…

This study looks at the long-term safety of a drug called guselkumab in children with moderate to severe Crohn's disease, ulcerative colitis, or juvenile psoriatic arthritis. About 196 kids who have already benefited from guselkumab in a previous study will continue receiving it.…

This study looks at how tiny plastic particles (microplastics) in our environment might affect gut health and inflammation, especially in pregnant women and their families. Researchers will measure microplastics in stool samples and study the gut bacteria of 46 participants. The …

This study includes 50 adults with Crohn's disease who have a permanent ileostomy. Researchers will review routine endoscopy videos and interview participants to create new tools that measure inflammation and symptoms. The goal is to help this group be included in future clinical…

This study looks at how much energy, water, and waste are produced by different ways of imaging the bowel in people with ulcerative colitis or Crohn's disease. It compares a non-invasive ultrasound method with standard colonoscopy and CT scans. The goal is to see if the ultrasoun…

This study looks at how often people with Crohn's disease, ulcerative colitis, an ileostomy, or bile acid diarrhea have low magnesium levels. Magnesium is important for muscles, nerves, and heart health, but standard blood tests may miss a deficiency. Researchers will compare dif…