Amish volunteers help unlock genetic secrets of diabetes drug

NCT ID NCT02891954

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This study looks at how a person's genes might change the way their body responds to canagliflozin, a drug used for type 2 diabetes. Healthy volunteers of Amish descent will take the drug for five days, and researchers will measure how much sugar comes out in their urine and check other health markers. The goal is to find genetic clues that could help doctors predict who will benefit most from this medication.

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