Genetic test aims to stop drug side effects before they start

NCT ID NCT06322238

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a genetic test can help doctors choose safer drugs and doses for 39 common medications. 66 adults getting a new prescription will receive the test, and researchers will track side effects like muscle aches, fainting, or mood changes for 48 weeks. The goal is to see if this approach reduces harmful drug reactions in everyday primary care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pharmacogenetic (PGx) panel test

What this could lead to

If successful, this could show that a simple genetic test before prescribing common drugs reduces side effects and improves treatment in everyday primary care.

What could go wrong

This is a small, early-phase study at one health system, so results may not apply broadly. The test may not prevent all side effects, and some risks are still possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Drug Metabolism, Poor, CYP2C19-Related Drug Metabolism, Poor, CYP2D6-Related

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55902, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••