Personalized brain zaps: a new hope for tough depression?

NCT ID NCT07528157

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a brain stimulation treatment for depression called iTBS can be improved by customizing it to each person's brain signals. Researchers will use EEG to measure brain responses and find the best stimulation settings for 80 adults with treatment-resistant depression. The goal is to see if personalized settings work better than standard ones.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intermittent theta burst stimulation (iTBS) delivered via a device

What this could lead to

If successful, this could point toward a more effective, personalized way to treat depression that doesn't respond to standard treatments.

What could go wrong

This is an early-stage study focused on measuring brain signals, not yet testing if the personalized treatment actually improves depression symptoms. The approach may not translate into better outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford University

    Stanford, California, 94305, United States