Can better CPR save more kids? largest study launches

NCT ID NCT02708134

Recruiting now Knowledge-focused Sponsor: Children's Hospital of Philadelphia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study watches how doctors and nurses perform CPR on children who have had a cardiac arrest. Researchers will check if following American Heart Association guidelines for chest compression depth, rate, and timing leads to better outcomes. Up to 7,000 children across multiple hospitals will be included. The goal is to find out which CPR techniques work best to improve survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could identify which CPR techniques work best for children, leading to improved resuscitation guidelines.
What could go wrong: This is an observational study, so it cannot prove cause and effect. Results may not apply to all hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC ARREST CARDIOPULMONARY ARREST

Contacts and locations

Locations

Aichi Children's Health and Medical Center
RECRUITING

Aichi, 474-8710, Japan
Akron Children's
RECRUITING

Akron, Ohio, 44308, United States
Albany Medical Center
RECRUITING

Albany, New York, 12208, United States
Alberta Children's
RECRUITING

Calgary, AB T3B, Canada
All Children's Hospital
NOT_YET_RECRUITING

St. Petersburg, Florida, 33701, United States
BC Children's
RECRUITING

Vancouver, British Columbia, V6H 3N1, Canada
Boston Children's
RECRUITING

Boston, Massachusetts, 02115, United States
Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Children's Colorado
RECRUITING

Aurora, Colorado, 80045, United States
Children's Healthcare of Atlanta (CHOA)
RECRUITING

Atlanta, Georgia, 30322, United States
Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Children's Hospital of Richmond at VCU
RECRUITING

Richmond, Virginia, 23219, United States
Chldren's Hospital of Orange County
RECRUITING

Orange, California, 92868, United States
Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States
Cohen Children's Medical Center
RECRUITING

Queens, New York, 11040, United States
Dartmouth Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
Dell Children's Medical Center
RECRUITING

Austin, Texas, 78723, United States
Erasmus MC - Sophia Children's
RECRUITING

Rotterdam, 3015, Netherlands
Great Ormond Street Hospital
RECRUITING

London, WC1N 3JH, United Kingdom
Gregorio Marañón General University Hospital
RECRUITING

Madrid, 46 28007, Spain
IRCCS Ospedale Pediatrico Bambino Gesù
RECRUITING

Roma, 486686, Italy
Instituto Roosevelt
RECRUITING

Bogotá, Colombia
KK Women's & Children's Hospital
RECRUITING

Singapore, 229899, Singapore
Kaiser Permanente
RECRUITING

Los Angeles, California, 90027, United States
Kentucky Children's Hospital
RECRUITING

Lexington, Kentucky, 40536, United States
King Chulalongkorn University
RECRUITING

Bangkok, 10330, Thailand
Kobe Children's Hospital (Hyogo Prefectural)
RECRUITING

Kobe, 650-0047, Japan
Lurie Children's (Children's Hospital of Chicago)
RECRUITING

Chicago, Illinois, 60611, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Medical City Children's Hospital
RECRUITING

Dallas, Texas, 75230, United States
Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina
NOT_YET_RECRUITING

Charleston, South Carolina, United States
Morgan Stanley Children's Hospital
RECRUITING

New York, New York, 10032, United States
Mount Sinai Kravis Children's Hospital
RECRUITING

New York, New York, 10029, United States
National Taiwan University Hospital
RECRUITING

Taipei, 100229, Taiwan
National University Hospital
RECRUITING

Singapore, 119074, Singapore
Nationwide Children's Hospital
RECRUITING

Columbus, Ohio, 43205, United States
Nebraska Medical Center
RECRUITING

Omaha, Nebraska, United States
Nemours Children's Hospital
RECRUITING

Wilmington, Delaware, 19803, United States
Perth Children's Hospital
RECRUITING

Nedlands, 6009, Australia
Queensland Children's Hospital
RECRUITING

South Brisbane, 4101, Australia
Rady Children's Hospital
RECRUITING

San Diego, California, 92123, United States
Riley Hospital for Children
RECRUITING

Indianapolis, Indiana, 46202, United States
Sabara Hospital Infantil
RECRUITING

São Paulo, 01227-200, Brazil
Seattle Children's Hospital
RECRUITING

Seattle, Washington, 98105, United States
Seoul National University Bundang Hospital
RECRUITING

Seongnam, 13620, South Korea
St. Louis Children's Hospital
RECRUITING

St Louis, Missouri, 63110, United States
Stanford University
RECRUITING

Palo Alto, California, 94304, United States
Starship Children's Hospital
RECRUITING

Auckland, 1023, New Zealand
Stollery Children's Hospital
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
Stony Brook University Hospital
RECRUITING

Stony Brook, New York, 11794, United States
The Children's Hospital at Westmead
RECRUITING

Westmead, New South Wales, 2145, Australia
The Children's Hospital of San Antonio
RECRUITING

San Antonio, Texas, 78207, United States
The Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
Tokyo Metropolitan Children's Medical Center
RECRUITING

Tokyo, 183-8561, Japan
University of Chicago, Comer Children's Hospital
RECRUITING

Chicago, Illinois, 60637, United States
University of Iowa Stead Family Children's Hospital
RECRUITING

Iowa City, Iowa, 52242, United States
University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27514, United States
University of Texas Southwestern
RECRUITING

Dallas, Texas, 75390, United States
Upstate Golisano Children's Hospital
RECRUITING

Syracuse, New York, 13210, United States
Valley Children's Hospital
RECRUITING

Madera, California, 93636, United States

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