New weekly shot shows promise for obesity in early trial

NCT ID NCT06350812

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new drug called PB-119, given as a weekly injection, in 32 Chinese adults with obesity. The main goal was to check safety and how the body processes the drug, but researchers also looked at weight loss. Participants were randomly assigned to receive either PB-119 or a placebo, and neither they nor the doctors knew who got which. The trial is complete, but results are not yet published.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PB-119 (a weekly injection)
What this could lead to
If successful, PB-119 could become a new option for helping people with obesity lose weight safely.
What could go wrong
This is an early trial with only 32 participants, so results may not apply to everyone. Side effects and long-term safety are still unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Third XIANGYA Hospital of Central South University

    Changsha, Hunan, 410013, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.