Leg movement may predict heart risk in seniors

NCT ID NCT03625349

Ongoing Diagnosis Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether a simple, non-invasive leg movement test can measure blood vessel health in older adults. Researchers will use ultrasound to track blood flow changes after a passive leg movement, comparing young healthy people and older patients undergoing heart tests. The goal is to create a practical tool for assessing vascular health and guiding rehabilitation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NG-Monomethyl-L-Arginine (LNMMA)
What this could lead to: If successful, this simple leg-movement test could become a standard way to check blood vessel health and guide personalized rehab for older adults.
What could go wrong: This is an early-stage study with only 130 participants, so results may not apply to everyone. The test is still experimental and not yet proven for routine clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AGING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING CARDIOVASCULAR DISEASE

Contacts and locations

Locations

VA Salt Lake City Health Care System, Salt Lake City, UT

Salt Lake City, Utah, 84148-0001, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.