Leg movement may predict heart risk in seniors

NCT ID NCT03625349

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether a simple, non-invasive leg movement test can measure blood vessel health in older adults. Researchers will use ultrasound to track blood flow changes after a passive leg movement, comparing young healthy people and older patients undergoing heart tests. The goal is to create a practical tool for assessing vascular health and guiding rehabilitation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NG-Monomethyl-L-Arginine (LNMMA)

What this could lead to

If successful, this simple leg-movement test could become a standard way to check blood vessel health and guide personalized rehab for older adults.

What could go wrong

This is an early-stage study with only 130 participants, so results may not apply to everyone. The test is still experimental and not yet proven for routine clinical use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • VA Salt Lake City Health Care System, Salt Lake City, UT

    Salt Lake City, Utah, 84148-0001, United States