Treadmill training may slow Parkinson's by fighting inflammation
NCT ID NCT05815524
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether intensive treadmill exercise can improve motor symptoms and reduce inflammation in people with early-stage Parkinson's disease. Researchers measured changes in movement scores and blood markers of nerve damage and inflammation in 30 patients who either exercised or continued their usual routine. The goal was to see if physical activity could act as a disease-modifying approach, but the study was terminated early, so results are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
treadmill training
What this could lead to
If successful, this could point toward physical activity as a way to slow Parkinson's progression by reducing inflammation and supporting brain health.
What could go wrong
The study was terminated early and enrolled only 30 people, so results are limited. It is not a treatment and may not apply to all Parkinson's patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Flavia Torlizzi
Roma, 00168, Italy