Parkinson's gene study links sleep problems to worse symptoms
NCT ID NCT04553185
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 733 people with Parkinson's disease to see if certain genetic variations in the AQP4 gene are linked to worse motor, cognitive, and sleep symptoms. Participants provided blood samples, wore sleep monitors, and completed online tests. The goal is to better understand how genes and sleep problems relate to Parkinson's progression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help identify genetic markers that predict worse symptoms in Parkinson's disease, potentially guiding personalized care.
What could go wrong
This is an observational study, not a treatment trial. It only looks for associations, so it cannot prove cause and effect or lead directly to new therapies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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East Kent University Hospitals NHS Foundation Trust
Ashford, United Kingdom
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Lewisham and Greenwich NHS Foundation Trust
London, United Kingdom
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Prince Phillip Hospital
Llanelli, United Kingdom
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University of Exeter
Exeter, SE16 7RJ, United Kingdom