Brain scans reveal how DBS impacts Parkinson's symptoms

NCT ID NCT06998303

Recruiting now Knowledge-focused Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses MRI scans to see how deep brain stimulation (DBS) changes brain activity in people with Parkinson's disease. Researchers will compare brain images when the stimulator is on versus off, focusing on the leg area of the brain. The goal is to understand why DBS sometimes fails to help with walking and balance problems, so doctors can improve programming for better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bipolar deep brain stimulation (DBS)
What this could lead to: If successful, this study could help doctors better program DBS devices to improve walking and balance problems in Parkinson's disease.
What could go wrong: This is a small, early-stage imaging study with only 20 participants, so results may not apply to everyone. It is not testing a new treatment, only observing brain activity.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55414, United States

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