Could a few minutes of special breathing help Parkinson's patients speak louder and move better?
NCT ID NCT07674264
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This pilot study tests whether a single session of breathing air with slightly higher carbon dioxide and lower oxygen can improve speech, cough, and movement in people with Parkinson's disease. Participants are randomly assigned to one of two breathing patterns, each lasting about 30 minutes. The goal is to see if these brief exposures can temporarily boost upper airway and motor function, and to explore which biological markers might predict who responds best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Acute intermittent hypercapnic hypoxia (AIHH) or acute intermittent hypercapnic normoxia (AIHN)
What this could lead to
If it works, this could point toward a non-drug, breathing-based therapy to improve speech, cough, and mobility in Parkinson's disease.
What could go wrong
This is a small, early pilot study with only 32 participants and a single session of treatment. Results may not apply to daily life or long-term use.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Norman Fixel Institute for Neurological Diseases
RECRUITINGGainesville, Florida, 80303-2181, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida
RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••