Could a drug make stem cell transplants safer for blood cancer patients?

NCT ID NCT02356159

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 31 times

Summary

This study tested whether the drug palifermin could make stem cell transplants from unrelated donors safer and more effective for people with blood cancers like leukemia or lymphoma. 34 adults received palifermin before transplant to see if it would reduce severe graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. The goal was to improve immune recovery and overall outcomes after transplant.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • National Marrow Donor Program

    Minneapolis, Minnesota, 55401, United States

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.