NON-HODGKIN'S LYMPHOMA

This early-stage trial is testing a new drug called ABBV-291 in adults with Non-Hodgkin's lymphoma that has come back or stopped responding to treatment. The study will first find the safest dose, then check if the drug can shrink tumors. About 165 participants will take part wor…

This study compares immunoglobulin (given through a vein or under the skin) with antibiotics to see which better prevents severe infections in people with blood cancers like myeloma, lymphoma, or leukemia who have low antibody levels. About 900 adults will take part. The goal is …

This early study tests a new treatment called KSVCBD for people with a type of blood cancer called B-cell non-Hodgkin's lymphoma that has come back or not responded to other treatments. KSVCBD is a special therapy that works inside the body to help immune cells attack cancer cell…

This program offers early access to venetoclax, a targeted cancer pill, for people with certain blood cancers like CLL, AML, and multiple myeloma. It is for patients who have no other suitable treatment options and cannot join ongoing clinical trials. A doctor must decide if the …

This study is testing an improved method for cord blood transplants in adults with high-risk blood cancers like leukemia and lymphoma. The goal is to see if this optimized approach helps more people survive and recover with fewer side effects. About 54 participants will receive t…

This study tests whether a combination of three drugs (etoposide, cytarabine, and PEG-rhG-CSF) works better than standard chemotherapy at collecting enough stem cells for a transplant in people with non-Hodgkin's lymphoma. About 99 participants who are in remission will be random…

This study tests a new way to make immune cells (T cells) that can find and attack cancer cells infected with the Epstein-Barr virus (EBV). The cells are made faster in the lab and given to patients with Hodgkin or non-Hodgkin lymphoma, or related diseases that have come back or …

This study tests a new drug called GNC-035 in 40 adults with non-Hodgkin lymphoma that has returned or not improved after standard therapy. The drug is a tetra-specific antibody designed to attack cancer cells in multiple ways. The goal is to find a safe dose and see if it can sh…

This study tests a program called Nite2Day+ that uses mindfulness and sleep tips to help people with blood cancers sleep better and manage fatigue, stress, and pain. About 60 adults hospitalized for treatment will either get the program or standard care. The program includes a mo…

This study tracks 100 patients taking newer BTK inhibitor drugs (acalabrutinib or zanubrutinib) for blood cancers like leukemia or lymphoma. Researchers want to find out how often these drugs cause heart rhythm problems or high blood pressure, and who is most at risk. Participant…

This study is a large registry that will collect medical information and biological samples from up to 10,000 adults with acute lymphoblastic leukemia (ALL) and certain related blood cancers. The goal is to track how patients are diagnosed, treated, and how they fare over time, i…

This study is collecting medical information from 2000 people with advanced mycosis fungoides or Sézary syndrome, two rare types of skin lymphoma. The goal is to create a tool that helps doctors predict which patients are at higher or lower risk, so they can tailor treatments mor…

This study gathers basic health information from 2000 people receiving stem cell transplants for blood cancers or immune disorders. The goal is to track survival and complications to help doctors and researchers improve future treatments. Participants must be getting a standard t…

This study collects tumor samples and medical information from people with lymphoma or related blood cancers who have a family history of these diseases. Researchers want to find genetic changes that may increase the risk of developing lymphoma. Participants provide blood or tiss…