Could ozone be the key to easing knee arthritis pain?
NCT ID NCT07678996
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study tests whether injecting ozone gas into the knee joint, combined with exercise, can reduce pain and improve function in people aged 40-75 with moderate knee osteoarthritis. Participants receive three weekly ozone injections at different concentrations (10, 15, or 20 µg/mL) plus a home exercise program, or exercise alone. The goal is to find the most effective dose for symptom relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ozone
What this could lead to
If effective, ozone injections could offer a non-surgical option to reduce pain and improve mobility in people with knee osteoarthritis.
What could go wrong
This is a small, early-stage trial with 80 participants, so results may not apply widely. Ozone injections may cause discomfort or infection, and the benefit over exercise alone is unproven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Kayseri City Hospital
RECRUITINGKayseri, 38080, Turkey (Türkiye)
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact