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Can common painkillers ease Parkinson's nerve pain? new study investigates.

NCT ID NCT02601586

Completed Symptom relief Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether two drugs, oxycodone (a strong painkiller) and levodopa (a Parkinson's medication), can reduce nerve pain caused by Parkinson's disease. 67 adults with Parkinson's and chronic nerve pain took one of the drugs or a placebo for 8 weeks, alongside their usual treatment. The goal was to see if either drug could lower average pain intensity better than a placebo.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

  • CHU Amiens

    Amiens, 80054, France

  • Chu Toulouse

    Toulouse, 31059, France

  • Henri Mondor Hospital

    Créteil, 94010, France

  • Hospital Pierre Wertheimer

    Lyon, France

  • Hospital of Aix-en-Provence

    Aix-en-Provence, 13616, France

  • Pitié-Salpêtrière Hospital

    Paris, 75651, France

  • University Hospital of Bordeaux

    Bordeaux, 33076, France

  • University Hospital of Clermont-Ferrand

    Clermont-Ferrand, 63003, France

  • University Hospital of Lille

    Lille, 59037, France

  • University Hospital of Limoges

    Limoges, 87042, France

  • University Hospital of Marseille

    Marseille, 13385, France

  • University Hospital of Nancy

    Nancy, France

  • University Hospital of Nantes

    Nantes, France

  • University Hospital of Nîmes - Caremeau

    Nîmes, France

  • University Hospital of Poitiers

    Poitiers, 86021, France

  • University Hospital of Rennes

    Rennes, 35033, France

  • University Hospital of Rouen

    Rouen, 76031, France

  • University Hospital of Strasbourg

    Strasbourg, 67098, France

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