Could a simple pill before heart surgery cut opioid use?
NCT ID NCT07221617
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 21 times
Summary
This study compares giving oral methadone before heart surgery versus intravenous methadone during anesthesia to see which better controls pain afterward. About 100 adults having elective heart surgery will take part at Mayo Clinic. The goal is to reduce the total amount of opioids needed in the first 72 hours after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-••••
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