Could cannabis oil ease chronic pain? small trial aims to find out

NCT ID NCT05351905

Completed Symptom relief Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This pilot study tested an oral cannabinoid oil (CBD with a small amount of THC) in 51 adults with chronic pain. The goal was to see if it's practical to run a larger trial and to gather early data on pain relief and safety. Participants took the oil daily for up to 12 weeks, and researchers tracked how many people completed the study and how well they stuck to the treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CBD oil (MPL-001) with a small amount of THC
What this could lead to: If successful, this could point toward a new treatment option for chronic pain that may help reduce opioid use.
What could go wrong: This is a small pilot study with only 51 participants, so results may not apply to everyone. It is designed mainly to test feasibility, not to prove the treatment works.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Chronic Pain chronic pain syndrome opioid abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS CHRONIC PAIN OPIOID USE

Contacts and locations

Locations

University Health Network

Toronto, Ontario, M5G 2C4, Canada

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