Double whammy for AFib: single procedure aims to fix rhythm and prevent strokes
NCT ID NCT06686485
First seen Jun 26, 2026 · Last updated Jul 24, 2026 · Updated 3 times
Summary
This study tests doing two heart procedures at the same time for people with atrial fibrillation. First, doctors use pulsed field energy to fix the heart's rhythm. Then, they implant a small device to close off a part of the heart where clots can form. The goal is to see if this combined approach is safe and works well. About 433 adults who need both treatments will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- FARAPULSE PFA system and WATCHMAN LAAC device
- What this could lead to
- If successful, this could show that combining two procedures in one session is safe and effective, simplifying treatment for atrial fibrillation patients.
- What could go wrong
- This is a mid-stage trial, so results may not confirm long-term benefits. There are risks from both the ablation and device implantation, including serious adverse events.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Nantong University
RECRUITINGNantong, China
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Asian Heart and Vascular Centre
RECRUITINGSingapore, Singapore
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Beijing Anzhen Hospital of the Capital University of Medical Sciences
RECRUITINGBeijing, China
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China Medical University Hospital
RECRUITINGTaichung, Taiwan
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First People's Hospital of Yunnan Province
RECRUITINGKunming, China
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Guangdong Nanfang Hospital
RECRUITINGGuangzhou, China
-
Huaxi Hospital of Sichuan University
ACTIVE_NOT_RECRUITINGChengdu, China
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Institute Jantung Negara
RECRUITINGKuala Lumpur, Malaysia
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Kawasaki Saiwai Hospital
RECRUITINGKawasaki, Japan
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Kokura Memorial Hospital
RECRUITINGFukuoka-ken, Japan
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Kurashiki Central Hospital
RECRUITINGKurashiki-shi, Okayama Kurashiki-shi, Japan
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National Taiwan University Hospital
RECRUITINGTaipei, Taiwan
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Osaka Keisatsu Hospital
RECRUITINGOsaka, Japan
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Prince of Wales Hospital
RECRUITINGHong Kong, Hong Kong
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Princess Margaret Hospital
RECRUITINGHong Kong, Hong Kong
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Pusat Jantung Sarawak
RECRUITINGKuching, Malaysia
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QiLu Hospital of ShanDong University
RECRUITINGJinan, China
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Queen Elizabeth Hospital
RECRUITINGKowloon, Hong Kong
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Queen Mary Hospital
RECRUITINGHong Kong, Hong Kong
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Saitama Red Cross Hospital
RECRUITINGSaitama, Saitama, Japan
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Sakakibara Heart Institute, Sakakibara Heart Foundation
RECRUITINGFuchu-shi, Tokyo, Japan
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Sendai Kousei Hospital
RECRUITINGSendai, Miyagi, Japan
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Shanxi Cardiovascular Hospital
RECRUITINGTaiyuan, China
-
Shonan Kamakura General Hospital
RECRUITINGKamakura-shi, Kanagawa, Japan
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Sir Run Run Shaw Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, China
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Taichung Veterans General Hospital
RECRUITINGTaichung, Taiwan
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Taipei Veterans General Hospital
RECRUITINGTaipei, Taiwan
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The Affiliated Hospital of Guizhou Medical University
RECRUITINGGuiyang, China
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The First Affiliated Hospital of Chengdu Medical College
RECRUITINGChengdu, China
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The First Affiliated Hospital of Soochow University
RECRUITINGSuzhou, Jiangsu, China
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The Third Affiliated Hospital of Guangzhou Medical University
RECRUITINGGuangzhou, China
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Toho University Ohashi Medical Center
RECRUITINGMeguro-ku, Japan
-
Xuanwu Hospital Capital Medical University
RECRUITINGBeijing, China
-
Yokohama city minato Red Cross Hospital
RECRUITINGYokohama, Japan
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Yokosuka Kyosai Hospital
RECRUITINGKanagawa, Japan
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Zhuhai People's Hospital
RECRUITINGZhuhai, China
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Zigong First People's Hospital
RECRUITINGZigong, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A tiny neck implant could catch Stroke-Causing clots before they reach the brain
- Could a new injection tame atrial fibrillation?
- Which blood thinner is safer for heart patients? a Head-to-Head test
- Can a cholesterol drug keep atrial fibrillation at bay after ablation?
- Can a One-Two punch fix a leaky heart valve and restore normal rhythm?
- Could a guided Self-Care plan tame atrial Fibrillation's return?