New study aims to cut opioid use after obesity surgery

NCT ID NCT03756961

Recruiting now Symptom relief Sponsor: Göteborg University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether replacing opioids with a non-opioid drug (dexmedetomidine) and adding person-centred care can improve recovery and reduce opioid use in 220 adults undergoing obesity surgery. Participants are randomly assigned to either the opioid-free approach or standard opioid-based care. The researchers will track pain, recovery, and opioid use for up to 24 months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine (a non-opioid sedative) and person-centred care
What this could lead to: If successful, this could offer a safer, opioid-free way to manage pain after obesity surgery, reducing side effects and long-term opioid use.
What could go wrong: This is a relatively small, non-blinded study, so results may not apply broadly. The opioid-free approach may not control pain as effectively as standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY PAIN, POSTOPERATIVE

Contacts and locations

Locations

Lindesberg Hospital
RECRUITING

Lindesberg, Region Örebro, 711 82, Sweden
Sahlgrenska University hospital/ Östra hopsital
RECRUITING

Gothenburg, VG, 41678, Sweden

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