New study aims to cut opioid use after obesity surgery
NCT ID NCT03756961
First seen Jan 08, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tests whether replacing opioids with a non-opioid drug (dexmedetomidine) and adding person-centred care can improve recovery and reduce opioid use in 220 adults undergoing obesity surgery. Participants are randomly assigned to either the opioid-free approach or standard opioid-based care. The researchers will track pain, recovery, and opioid use for up to 24 months after surgery.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Lindesberg Hospital
RECRUITINGLindesberg, Region Örebro, 711 82, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sahlgrenska University hospital/ Östra hopsital
RECRUITINGGothenburg, VG, 41678, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine (a non-opioid sedative) and person-centred care
What this could lead to
If successful, this could offer a safer, opioid-free way to manage pain after obesity surgery, reducing side effects and long-term opioid use.
What could go wrong
This is a relatively small, non-blinded study, so results may not apply broadly. The opioid-free approach may not control pain as effectively as standard care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.