Opioid study aims to personalize pain treatment for back pain sufferers
NCT ID NCT02824276
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how oral opioids like oxycodone or morphine affect pain sensitivity in 35 adults with chronic low back pain. Participants received either the opioid or a placebo to measure changes in pain perception. The goal is to understand individual differences and improve how doctors prescribe painkillers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Oxycodone or morphine sulfate immediate release (MSIR)
- What this could lead to
- If successful, this could help doctors tailor opioid prescriptions to individual patients for better pain relief.
- What could go wrong
- This is a small, early-phase study with only 35 participants, so results may not apply to everyone. Opioids also carry risks like addiction and side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02467, United States
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