Opioid study aims to personalize pain treatment for back pain sufferers
NCT ID NCT02824276
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how oral opioids like oxycodone or morphine affect pain sensitivity in 35 adults with chronic low back pain. Participants received either the opioid or a placebo to measure changes in pain perception. The goal is to understand individual differences and improve how doctors prescribe painkillers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oxycodone or morphine sulfate immediate release (MSIR)
What this could lead to
If successful, this could help doctors tailor opioid prescriptions to individual patients for better pain relief.
What could go wrong
This is a small, early-phase study with only 35 participants, so results may not apply to everyone. Opioids also carry risks like addiction and side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02467, United States