Heart transplant breakthrough? OCS device Follow-Up study tracks 5-Year survival

NCT ID NCT05741723

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study follows 276 heart transplant patients who received a donor heart preserved with the OCS Heart device. Researchers will track survival and other outcomes for up to 5 years after transplant. The goal is to confirm the long-term safety and effectiveness of using OCS-preserved hearts for transplantation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

OCS Heart device (preserves donor hearts for transplant)

What this could lead to

If successful, this study could confirm that OCS-preserved hearts are safe and effective for transplantation, potentially increasing the donor heart supply.

What could go wrong

This is a follow-up study, not a new treatment test. It only observes outcomes in already transplanted patients, so it cannot prove new benefits or safety beyond what is already known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AdventHealth Orlando

    Orlando, Florida, 32803, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Emory University Hospital

    Atlanta, Georgia, 30322, United States

  • Froedtert & the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • Minneapolis Heart Institute

    Minneapolis, Minnesota, 55407, United States

  • Montefiore

    The Bronx, New York, 10467, United States

  • Northwestern Medicine

    Chicago, Illinois, 60611, United States

  • Nyph/Cumc

    New York, New York, 10032, United States

  • Sentara

    Norfolk, Virginia, 23502, United States

  • St. Vincent Cardiovascular Research Institute

    Indianapolis, Indiana, 46260, United States

  • Stanford University

    Palo Alto, California, 94304, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • University of California San Diago

    La Jolla, California, 92037, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55414, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Wisconsin

    Madison, Wisconsin, 53792, United States

  • Vanderbilt Medical Center

    Nashville, Tennessee, 37232, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06510, United States