Personalized weight loss: Gene-Tailored drug shows promise
NCT ID NCT03525002
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a drug called bromocriptine, which boosts dopamine in the brain, can help people with obesity lose weight. The key twist: the drug's effect may depend on a person's genetic makeup, specifically a gene called FTO. 120 obese adults were given either bromocriptine or a placebo for 18 weeks, and researchers tracked weight changes and brain responses to food cues.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Cologne
Cologne, Germany
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University Hospital Luebeck
Lübeck, Germany
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University of Tuebingen, Department of Internal Medicine IV
Tübingen, 72076, Germany
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