Obesity's hidden role in kidney stones revealed?
NCT ID NCT04333745
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how obesity changes the way the body handles oxalate, a substance that can form kidney stones. Researchers will give 22 calcium oxalate stone formers a controlled low-oxalate diet and a special tracer to measure oxalate absorption, kidney handling, and natural production. The goal is to understand why obese people are more prone to kidney stones.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Controlled low oxalate diet and carbon-13 oxalate with sucralose
What this could lead to
If successful, this could help explain why obese people form more kidney stones and point toward better dietary advice or treatments to prevent stones.
What could go wrong
This is a small, early-stage observational study with only 22 participants, so results may not apply to everyone. It does not test a new treatment, only measures metabolism.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35243-3353, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States