Brain fog after COVID: could a kitchen oil be the answer?
NCT ID NCT05705648
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This trial tests whether a daily dose of medium chain triglyceride oil can ease brain fog in adults aged 22–50 with long COVID. Participants take either the active oil or a placebo (safflower oil) for several weeks and complete computer-based cognitive tests and questionnaires. The study aims to see if the oil improves thinking and memory complaints that persist after a COVID infection.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- medium chain triglyceride oil
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help clear brain fog in people with long COVID.
- What could go wrong
- This is a small, early-stage trial with no blinding, so results may be due to placebo effects. The supplement may have no benefit over the control oil.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
103 people
The number who actually took part.
- Started
-
Oct 2023
- Expected to finish
-
Mar 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
22 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * confirmed COVID infection, at least 3 months previously, with ongoing cognitive complaints * all other medical conditions stable, and on stable doses of medications (if required) Exclusion Criteria: * COVID infection not confirmed by PCR or Rapid test * unable to speak English * pre-COVID cognitve complaints, and/or medical diagnoses affecting cognitive function
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Alberta
Edmonton, Alberta, T6G 2P4, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Mindfulness may offer relief for long COVID sufferers
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- Beetroot juice: a natural boost against long COVID fatigue?
- A One-Two punch for long COVID? supplement and therapy put to the test