Eating your way to a sharper mind: new study tests diet against dementia
NCT ID NCT06853405
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a program of group nutrition classes, physical activities like walking and gardening, and at-home cognitive training can help prevent cognitive decline in older adults at higher risk for dementia. Researchers will enroll 120 people aged 55-85 and track changes in diet, quality of life, and memory complaints over the course of the intervention.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nutrition-based lifestyle intervention (group sessions, cognitive training, clinical nutrition consultations)
- What this could lead to
- If it works, this could point toward a practical, non-drug way to reduce dementia risk in older adults.
- What could go wrong
- This is a small early-stage trial (120 people) testing feasibility, not proof of effectiveness. Results may not apply to everyone, and adherence to the program may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged from 55 to 85 years old; * At least 4 years in the regular school system; * Higher individual risk for dementia defined as a score ≥6 points on the Cardiovascular Risk Factors, Aging and Dementia Dementia Risk Score (CAIDE). Exclusion Criteria: * Montreal Cognitive Assessment (MoCA) score lower than the validated cutoff points defined as 2 standard deviations below the normative reference value for the corresponding age and education in the Portuguese population; * Having a medical condition limiting the participation in the intervention (e.g., blindness, amputation…); * Lack of autonomy in daily activities; * Diagnosis of dementia or major incapacity.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Nutrition and Food Sciences, University of Porto
RECRUITINGPorto, 4150-180, Portugal
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Instituto de Saúde Pública da Universidade do Porto
RECRUITINGPorto, Portugal, 4000-600, Portugal
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