New pill aims to tackle obesity and diabetes by calming inflammation

NCT ID NCT07055516

Completed Disease control Sponsor: NodThera Limited Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study tests an experimental drug called NT-0796 in 176 obese adults, some with type 2 diabetes. Participants take the drug or a placebo alongside a reduced-calorie diet and increased physical activity for 6 months. The goal is to see if the drug helps with weight loss and reduces inflammation, which is linked to diabetes complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NT-0796 (oral capsule)
What this could lead to: If it works, this could point toward a new weight-loss and anti-inflammatory treatment for obesity and type 2 diabetes.
What could go wrong: This is an early Phase 2a trial with only 176 participants, so results may not apply to everyone. The drug is still experimental and may not prove effective or safe.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY AND TYPE 2 DIABETES

Contacts and locations

Locations

Investigative Site

Hialeah, Florida, 33016, United States
Investigative Site

Jacksonville, Florida, 32216, United States
Investigative Site

Miami, Florida, 33147, United States
Investigative Site

Port Orange, Florida, 32127, United States
Investigative Site

Columbus, Ohio, 43213, United States
Investigative Site

Dallas, Texas, 75230, United States
Investigative Site

Manassas, Virginia, 20110, United States
Investigative Sites

Marrero, Louisiana, 70006, United States
Investigative site

Mesa, Arizona, 85225, United States
Investigative site

Los Angeles, California, 90057, United States
Investigative site

Cooper City, Florida, 33024, United States

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