New hope for infertile men: drug combo may spark sperm production
NCT ID NCT06706414
First seen Jan 05, 2026 · Last updated Apr 29, 2026 · Updated 18 times
Summary
This study tests whether two drugs, denosumab and letrozole, can help men with a specific type of infertility (non-obstructive azoospermia) produce sperm. The trial includes 16 men who have no sperm in their semen and meet certain criteria, like a specific blood marker (AMH). The main goal is to see if sperm appears in semen or testicular tissue after 90 days of treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Division of Translational Endocrinology, Department of Endocrinology and Internal Medicine, Herlev and Gentofte Hospital
Herlev, 2730, Denmark
Conditions
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