Could a Man's own stem cells restore his fertility?
NCT ID NCT02641769
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This trial tests whether injecting a man's own purified stem cells into his testicles can restart sperm production. It is for men with non-obstructive azoospermia, a condition where the testicles produce little or no sperm. The stem cells are taken from the patient's bone marrow, purified, and then injected directly into the seminiferous tubules. The study will follow participants for 24 months to check for sperm in semen or testicular tissue and to monitor safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
autologous bone marrow-derived stem cells (spermatogonial and mesenchymal)
What this could lead to
If successful, this approach could help men with certain types of infertility produce their own sperm, potentially enabling biological fatherhood without donor sperm.
What could go wrong
This is an early-phase study (Phase 1/2) with 600 participants, so results are not yet proven. Risks include infection, bleeding, or failure to produce viable sperm.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Stem Cells of Arabia
RECRUITINGAmman, Amman Governorate, 11953, Jordan
Contact Phone: •••-•••-•••• Email: •••••@•••••