Could a weekly pill help men with no sperm become fathers?
NCT ID NCT07571928
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests a drug called leflutrozole in 15 men who have no sperm in their semen due to a blockage-free cause. The drug is taken as a weekly capsule and aims to boost sperm production. Researchers will check if sperm appear in the semen after 12-20 weeks of treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
leflutrozole (a drug that blocks estrogen production)
What this could lead to
If it works, this could point toward a new treatment for some men with infertility due to low sperm production.
What could go wrong
This is a very early, small trial with only 15 men. It may not work, and the drug could have side effects. Success is far from guaranteed.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Division of Translational Endocrinology, Department of Endocrinology and Internal Medicine, Copenhagen University Hospital Herlev., Herlev,
Herlev, 2100, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••