Tiny implant in vein could keep heart failure patients out of hospital

NCT ID NCT07574593

Recruiting now Disease control Sponsor: Foundry Innovation & Research 1, Limited (FIRE1) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This study tests a small sensor implanted in a large vein near the heart to help doctors monitor fluid buildup in people with heart failure. The sensor sends daily readings so treatment can be adjusted early. The trial will compare standard care plus sensor guidance to standard care alone in 800 patients, looking at whether it reduces heart failure events and deaths.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: implanted inferior vena cava sensor
What this could lead to: If successful, this sensor could help doctors better manage fluid levels in heart failure patients, potentially reducing hospital visits and improving survival.
What could go wrong: This is a large trial but still experimental. The sensor requires a procedure to implant, which carries risks like infection, blood clots, or device movement. It may not prove better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure mild heart failure moderate heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE NYHA CLASS II HEART FAILURE NYHA CLASS III HEART FAILURE

Contacts and locations

Locations

Baycare Health System
RECRUITING

Tampa, Florida, 33607, United States
Cardiovascular Institute of San Diego
RECRUITING

Chula Vista, California, 91911, United States
Christ Hospital Lindner
RECRUITING

Cincinnati, Ohio, 45219, United States
North Central Heart - Avera Hospital
RECRUITING

Sioux Falls, South Dakota, 57108, United States
Saint Francis Health System
RECRUITING

Tulsa, Oklahoma, 74136, United States
UC Davis
RECRUITING

Sacramento, California, 95817, United States
University of Florida Health - Jacksonville
RECRUITING

Jacksonville, Florida, 32209, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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