Could direct heart pacing beat standard therapy for heart failure?
NCT ID NCT07492979
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study compares a newer pacing method (HIS or left bundle branch pacing) to the standard biventricular pacing in 1100 heart failure patients across Nordic countries. The goal is to see if the new approach reduces death or unplanned heart failure hospitalizations. Participants must have severe heart failure and a specific heart block pattern.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Conduction system pacing (HIS bundle or left bundle branch pacing) procedure
What this could lead to
If successful, this could offer a more effective pacing method for heart failure patients, potentially reducing deaths and hospital stays.
What could go wrong
This is a large trial but has not yet started recruiting. The new pacing technique may not prove superior and carries procedural risks like bleeding or lead complications.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dept of Cardiology, Meilahti Hospital, Helsinki
Helsinki, 00290, Finland
Contact Email: •••••@•••••
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Dept. of Cardiology, Aarhus University Hospital, Aarhus
Aarhus, 8200, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Haukeland Universitetssykehus
Bergen, 5009, Norway
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sahlgrenska University Hospital
Gothenburg, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••